BMP8B Antibody

Code: CSB-PA788463

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Size:

100μl

US$297

Quantity:

Species Reactivity: Human

Raised in: Rabbit

Application: ELISA,WB

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Target Background

Product Details

Uniprot NO.

P34820

Target Names

BMP8B

Alternative Names

BMP-8 antibody; BMP-8B antibody; BMP8 antibody; Bmp8b antibody; BMP8B_HUMAN antibody; bone morphogenetic protein 8 (osteogenic protein 2) antibody; Bone morphogenetic protein 8 antibody; Bone morphogenetic protein 8B antibody; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)) antibody; OP-2 antibody; OP2 antibody; Osteogenic protein 2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from internal of Human BMP8B.

Immunogen Species

Homo sapiens (Human)

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Tested Applications

ELISA,WB

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Images

Western blot analysis of extracts from 293 cells and A549 cells, using BMP8B antibody.

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Target Background

Function(From Uniprot)

Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.

Gene References into Functions

Acetylated H3K9 and H4K16 levels at BMP8B were increased in gastric cancer (GC) compared to nontumors (P < 0.05). However, reduced levels of acetylated H3K9 and H4K16 were associated with poorly differentiated GC (P < 0.05). PMID:27748538
Study found that BMP8B was downregulated in pancreatic cancer tissues and BMP8B mediates the survival of pancreatic cancer cells and regulates the progression of pancreatic cancer. PMID:25176058
Five novel SNPs within BMP8B gene.Genetic variants in BMP8B gene are associated with growth traits in Chinese native cattle. PMID:24076131
Epigenetic silencing of the bone morphogenetic protein 2 gene through methylation is associated with gastric carcinomas PMID:16314833
Reports on the mouse homolog of this gene. PMID:9070944