APRT Antibody

Code: CSB-PA001954GA01HU

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Size:

100μl

US$600

Quantity:

Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: ELISA,WB

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Target Background

Product Details

Uniprot NO.

P07741

Target Names

APRT

Alternative Names

Adenine phosphoribosyltransferase antibody; AMP antibody; AMP diphosphorylase antibody; AMP pyrophosphorylase antibody; APRT antibody; APT_HUMAN antibody; DKFZp686D13177 antibody; MGC125856 antibody; MGC125857 antibody; MGC129961 antibody; Transphosphoribosidase antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human APRT

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.

Gene References into Functions

A long TA repeat in the promoter region of IL28B was associated with spontaneous HCV clearance. PMID:25735432
A new mutation, p.Gln147X, in APRT gene, was found in a patient with adenine phosphoribosyltransferase deficiency. PMID:24986359
Case study of 2 year old Japanese boy with APRT deficiency. Genetic analysis showed compound heterozygote APRT*J and missense mutation L33P. APRT deficiency should be suspected in patients with radiolucent kidney stones and urinary 2,8-DHA crystals. PMID:21635362
kinetic, regulatory and thermostability properties of APRT from erythrocytes of HGPRT deficient patients PMID:14674717
determination of structure and examination of role of deficiency in DHA-urolithiasis PMID:15196008
two novel mutations, G133D and V84M, were found in the APRT gene in Japanese patients with APRT deficiency PMID:15571218
APRT assay in a sample of patient hemolysate showed no detectable activity of the enzyme (25.56+/-9.55 U/L red blood cells in control healthy subjects). PMID:17126311
Data indicates that the flexible loop structure adopts an open conformation before and after binding of both substrates adenine and phosphoribosyl pyrophosphate. PMID:18399692
The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP are reported. PMID:19399589