ACHE Antibody

Code: CSB-PA001154EA01BO
Size:
20μg
20μg50μg100μg
US$83
Quantity:
Species Reactivity: Bovine
Raised in: Rabbit
Application: ELISA
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Product Details

Uniprot NO.
Target Names
ACHE
Alternative Names
ACHEAcetylcholinesterase antibody; AChE antibody; EC 3.1.1.7 antibody
Raised in
Rabbit
Species Reactivity
Bovine
Immunogen
Recombinant Bovine Acetylcholinesterase protein (31-613AA)
Immunogen Species
Bos taurus (Bovine)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
ELISA
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
Gene References into Functions
  1. To date, AChE and BChE are the only proteins known that include polyproline tetramer organizing peptides in their tetrameric structure. PMID:23352838
  2. The monomeric form of AChE in fetal bovine serum is trimmed at the carboxyl-terminus compared to the tetrameric form, consistent with the involvement of C-terminal amino acids in the assembly of monomers into tetramers. PMID:14690439
  3. findings show that AChE induces a remarkable aggregation of PrP 106-126 with a mechanism similar to that described for amyloid beta protein PMID:16750169
  4. In this work, the catalytic activity of acetylcholinesterase (AChE) immobilized on these materials was investigated, using neostigmina as AChE inhibitor. PMID:17208293
  5. Results strongly support the role of acetylcholinesterase in triggering amyloidogenesis and the potential therapeutic relevance of peripheral site blocker compounds. PMID:19038345
  6. Hydrolysis of acetylthiocoline, o-nitroacetanilide and o-nitrotrifluoroacetanilide by fetal bovine serum acetylcholinesterase PMID:19292875

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Subcellular Location
Cell junction, synapse. Secreted. Cell membrane; Peripheral membrane protein.; [Isoform H]: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Protein Families
Type-B carboxylesterase/lipase family
Database Links

UNIGENE: Bt.1299

KEGG: bta:540446

STRING: 9913.ENSBTAP00000001517

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