AASS Antibody, FITC conjugated

Code: CSB-PA883373LC01HU

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50μg100μg

US$166

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Species Reactivity: Human

Raised in: Rabbit

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Target Background

Product Details

Uniprot NO.

Q9UDR5

Target Names

AASS

Alternative Names

AASSAlpha-aminoadipic semialdehyde synthase antibody; mitochondrial antibody; LKR/SDH) [Includes: Lysine ketoglutarate reductase antibody; LKR antibody; LOR antibody; EC 1.5.1.8); Saccharopine dehydrogenase antibody; SDH antibody; EC 1.5.1.9)] antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Alpha-aminoadipic semialdehyde synthase, mitochondrial protein (224-364AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively.

Gene References into Functions

GR and KLF15 physically interact via low affinity GR binding sites within glucocorticoid response elements (GREs) for PRODH and AASS that contribute to combinatorial regulation with KLF15. PMID:26088140
Mitochondrial NADPH is crucial for AASS function PMID:24847004
Hyperlysinemia is caused by mutations in AASS PMID:23570448
Isolation and characterization of the mouse ortholog. PMID:10567240