Abbreviation
Recombinant Human SAA1 protein (Active)
Purity
>98% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU/μg as determined by LAL method.
Activity
Fully biologically active when compared to standard. The biological activity determined by a chemoattract bioassay using human monocytes is in a concentration range of 10-100 ng/ml.
Alternative Names
SAA1; Serum amyloid A-1 protein; SAA) [Cleaved into: Amyloid protein A; Amyloid fibril protein AA); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(2-103); Serum amyloid protein A(2-102); Serum amyloid protein A(4-101)]
Species
Homo sapiens (Human)
Expression Region
19-122aa
Target Protein Sequence
RSFFSFLGEA FDGARDMWRA YSDMREANYI GSDKYFHARG NYDAAKRGPG GVWAAEAISD ARENIQRFFG HGAEDSLADQ AANEWGRSGK DPNHFRPAGL PEKY
Note: The complete
sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is
translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application,
please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full Length of Mature Protein
Tag Info
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Buffer
Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris-HCl, pH 9.0, 150 mM NaCl
Storage
Store at -20°C/-81°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Lead Time
Basically, we can dispatch the products out in 5-10 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Shelf Life
The shelf life is related to many factors, storage state, storage temperature and the stability of the product itself. Generally, the shelf life of lyophilized form is 6 months at -20°C/-80°C from the date of receipt.
Datasheet & COA
Please contact us to get it.
Description
SAA1 functions as an acute-phase reactant and chemoattractant whose plasma concentration can surge 1,000-fold during inflammation, making it a critical mediator in innate immunity and a biomarker for inflammatory disease states. This tag-free preparation spanning residues 19–122 demonstrates full biological activity in a monocyte chemoattraction bioassay at 10–100 ng/ml, providing a quantitative benchmark for cell migration studies and enabling researchers to dissect SAA1-driven recruitment pathways in models of infection, atherosclerosis, and tumor microenvironment biology. The endotoxin level of less than 1.0 EU/μg satisfies the purity and endotoxin criteria typical for immune cell activation assays, ensuring that observed responses—whether in NF-κB or MAPK signaling experiments—are attributable to SAA1 rather than LPS contamination. Purity exceeding 98% by SDS-PAGE, combined with the validated chemotactic potency, supports use in antibody development workflows where a homogeneous immunogen is essential for generating monospecific reagents.
