Recombinant Human Interleukin-13 (IL13) (Active)

In Stock
Code: CSB-AP004321HU
Size:
10ug
10ug50ug500ug1mg
US$290
Quantity:
Express system: Mammalian cell
Species: Homo sapiens (Human)
Tag Info: C-terminal 6xHis-tagged
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Product Details

Abbreviation
Recombinant Human IL13 protein, partial (Active)
Purity
Greater than 95% as determined by SDS-PAGE.
Endotoxin
Less than 0.01 EU/µg as determined by LAL method.
Activity
The ED50 as determined in a cell proliferation assay using TF‑1 human erythroleukemic cells is 1.5-4.5 ng/ml.
Target Names
IL13
Uniprot NO.
Research Area
Immunology
Alternative Names
Allergic rhinitis; ALRH; BHR 1; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13; IL-13; Il13; IL13_HUMAN; Interleukin 13; Interleukin-13; interleukin13; MGC116786; MGC116788; MGC116789; NC 30; NC30; P 600; P600
Species
Homo sapiens (Human)
Source
Mammalian cell
Expression Region
35-146aa
Target Protein Sequence
GPVPPSTALRELIEELVNITQNQKAPLCNGSMVWSINLTAGMYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRDTKIEVAQFVKDLLLHLKKLFREGQFN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Mol. Weight
13.4 kDa
Protein Length
Full Length of Mature Protein
Tag Info
C-terminal 6xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Buffer
Lyophilized from a 0.2 μm filtered PBS,PH7.4
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Troubleshooting and FAQs
Datasheet & COA
Please contact us to get it.
Images
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Description

IL-13 drives Th2-polarized immune responses and plays a central role in allergic inflammation, fibrosis, and alternative macrophage activation, making precise functional studies of this cytokine essential for immunology research. This recombinant human IL-13 (residues 35–146) carries a C-terminal 6xHis tag and demonstrates robust signaling potency with an ED50 of 1.5–4.5 ng/mL in TF-1 cell proliferation assays, confirming its suitability for cell-based functional studies including JAK/STAT6 pathway activation, B-cell differentiation, and macrophage polarization experiments. Endotoxin levels below 1.0 EU/μg minimize LPS-driven artifacts that can confound immune cell readouts, supporting use in sensitive in vivo inflammation models and as a reference standard in cytokine detection assays. Mammalian-expressed to preserve native folding and post-translational modifications, this protein provides greater than 95% purity and aligns with standards expected in antibody development workflows such as ELISA coating or positive control applications.

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