Rat Angiopoietin 2,ANG-2 ELISA Kit

1. Based on these findings, we propose that Cx43 was the Cx isoform involved in MEGJ-mediated VEC-dependent regulation of Ang-2, which induces iNOS protein expression and vascular hyporeactivity after hypoxia. PMID:28637680
2. H2S may play a protective role in infrarenal aortic clamping induced acute lung injury in rats by inhibiting inflammation and Ang2 release. PMID:26781077
3. Inhibition of angiopoietin-2 is an effective and safe treatment for liver fibrosis in CCl4 -treated rats, acting mainly through the induction of vessel normalization and the attenuation of hepatic inflammatory infiltrate. PMID:24612347
4. responsible for the vascular hyporeactivity at late hemorrhagic shock through the Tie2-Erk-iNOS pathway PMID:22869617
5. it is unlikely that induction of Ang-2 contributes to vascular dysfunction underlying functional impairment after spinal cord injury, but rather that it contributes to the beneficial pro-angiogenic and/or gliogenic processes PMID:22020092
6. Decreased angiopoietin1/Tie2 and increased angiopoietin2 expression may contribute to diabetes-induced vascular damage after stroke. PMID:21515377
7. Hyperoxia induced neovascularization and inhibited the expression of ang-2 in the retina. PMID:19573435
8. The expression of Ang-2 protein in serum was significantly positively correlated with the extent lung injury. PMID:19900368
9. Expression of angiopoietin-2 increased after stroke in all rat strains and was significantly enhanced in SHR stroke-prone compared with control strains PMID:11822892
10. These data suggest that Ang2 might modulate both angiogenesis and vascular regression in the rat brain and that capillary regression occurring during deadaptation involves activation of apoptosis. PMID:12183511
11. Expressed in rat brain during hypoxia and de-adaptation. PMID:12580449
12. we demonstrate that testicular vascular endothelial growth factor-A (VEGF-A), ang 1, ang 2, and the ang-receptor tie 2 are expressed in the testis PMID:12773423
13. Angiopoietin2 and Tie2, but not angiopoietin1 mRNA were increased with retinopathy of prematurity. PMID:12937129
14. Angiopoietin-1 but not angiopoietin-2 has a role in experimental glioma angiogenesis PMID:15509526
15. Following injury, Ang2 may play a role in BBB breakdown of perilesional vessels, and it may also be a factor in endothelial cell apoptosis that occurs at days 1 and 2 following the injury. PMID:16056241
16. Data demonstrate that vascular smooth muscle cells adjust angiopoietin-2 expression through multiple mechanisms, including changes in transcription as well as posttranscriptional mRNA destabilization. PMID:16176970
17. Up-regulation of Ang-2, a proangiogenic factor, and the down-regulation of PEDF, an antiangiogenic factor, is indicative of an imbalance between pro- and antiangiogenic factors in the hypoxic retina that may favor neovascularization. PMID:17943991
18. glomerular expression of ANG-1 and ANG-2 is differentially regulated and may contribute to healing and endothelial cell stabilization in experimental glomerulonephritis PMID:18272601
19. Abnormal expression and reciprocal egulation of Angpt2 may play important roles in the development of chronic allograft nephropathy in rat renal allografts. PMID:18929864
20. Ang2-derived tumor vessels lead to an inadequate oxygenation of the tumor tissue, leading to impairment in tumor growth PMID:19168695

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UNIGENE: Rn.138360

KEGG: rno:89805

STRING: 10116.ENSRNOP00000022774