Mouse intercellular adhesion molecule 1,ICAM-1 ELISA KIT

1. The present study demonstrated that IL-1b may induce ICAM-1 expression, thus enhancing the cohesion between mesenchymal stem cells and endothelial progenitor cells via the p38 MAPK signaling pathway. PMID:29393395
2. ICAM-1 overexpressing Mesenchymal Stem Cells could suppress Dendritic Cells maturation according to co-culture methods and suppress the T cell immune response according to the mixed lymphocyte response (MLR) and lymphoblast transformation test (LTT) tests. PMID:29763906
3. The results showed that MOVACs transfected with pCMV5-HA-RKIP significantly inhibited TNF-a induced mRNA and protein expression of ICAM-1 and VCAM-1. PMID:28983072
4. Endotoxaemia enhanced early venous thrombosis occurs in a TLR-4 and ICAM-1 dependent fashion, and is potentiated by neutropenia. PMID:27975098
5. Data show that intercellular adhesion molecule 1 (ICAM-1) and ICAM-2 on B cells are essential for long-lasting cognate T follicular helper (Tfh)-B cell interactions and efficient selection of low-affinity B cell clones for proliferative clonal expansion PMID:28939548
6. in T cells, PI3Kdelta attenuates the activation of Rac1, but sustains the activation of Rap1. PMID:26740009
7. PTPN22 colocalized with its substrates at the leading edge of cells migrating on surfaces coated with the LFA-1 ligand intercellular adhesion molecule-1 (ICAM-1). PMID:27703032
8. Blocking CD54 inhibited NK cell-mediated cytotoxicity of the GM-CSF-stimulated Flt3 ligand conventional dendritic cells. NK cell-mediated lysis of GM-CSF-stimulated cDCs was, in part, a result of increased expression of CD54. PMID:27034402
9. These results indicate that, whereas T cells use ICAM-1 and -2 for temporary pulmonary entrapment, neutrophils get sequestered and extravasate into inflamed lungs independent of ICAMs. PMID:26823454
10. This study indicates that the ANG II effects are, in part, mediated or triggered by Gal-3 together with the related intercellular signaling (ICAM-1 and IL-6), leading to cardiac inflammation and fibrosis. PMID:27496875
11. Data suggest CKIP1 (casein kinase 2 interacting protein-1) plays role in resistance to oxidative stress in glomerular mesangial cells in development of diabetic nephropathy; mechanisms appear to include down-regulation of expression of ICAM1 (intercellular adhesion molecule-1) and fibronectin plus activation of Nrf2/ARE (nuclear factor E2-related factor 2/antioxidant response element) antioxidative stress pathway. PMID:27481061
12. ICAM1 regulates pathological cardiac remodeling by mediating proinflammatory leukocyte infiltration in the left ventricle and cardiac fibrosis and dysfunction. PMID:27068635
13. Its antiatherogenic impact might be associated with a suppressed adhesion to the endothelium due to down-regulation of endothelial ICAM-1 expression. PMID:26717272
14. Luteolin may inhibit tumor angiogenesis and tumor cell proliferation by down-regulation of LFA- 3 and PCNA and up-regulation of ICAM-1 in tumor tissue of tumor-bearing mice, thereby achieving its anti-tumor effect. PMID:26600503
15. our results further highlight the pleiotropic role of ICAM-1 in T-cell-dependent immune responses, with a major role in Treg cell development and suppressive function. PMID:26370005
16. the present results shed light on regulation of expression and function of ICAM-1 on neutrophils and identify it as an additional regulator of neutrophil effector responses in host defense. PMID:26647392
17. we identified intracellular adhesion molecule (ICAM)-1, through fibrinogen binding, as a previously unreported mediator of platelet-monocyte interactions PMID:26215112
18. miR-222 was transported into recipient endothelial cells by endothelial microparticles and functionally regulated expression of its target protein ICAM-1 in vitro and in vivo. PMID:26081516
19. Timely blockade of ICAM-1.LFA-1 interaction prevents disease onset in a mouse model of emphysema. PMID:26098520
20. MRTF-A/B depletion results in an increase in the cell surface expression of ICAM-1 and interactions between HAoECs and leukocytes PMID:26024305
21. neutrophils are reliant on endothelial activation for adhesion, initially via E-selectin and subsequently, by integrin-mediated binding to ICAM-1 and VCAM-1, combined with CXCL8-dependent chemotaxis. PMID:26216937
22. Inhibition of the P2RX7 pathway not only decreased endothelial ICAM-1 expression and leukocyte adhesion but also prevented microglia overactivation, reduced brain injury, and consequently doubled the early survival of septic mice. PMID:25998681
23. ICAM-1 in the tumor microenvironment, via restraining efferocytosis of apoptotic tumor cells, can block M2 macrophage polarization through regulation of PI3K/AKT activation, which leads to prevention of tumor metastasis. PMID:26068788
24. Activation of Wnt/beta-catenin signaling in AECs attenuated intercellular adhesion molecule 1 (ICAM-1)/vascular cell adhesion molecule 1 (VCAM-1)-mediated adhesion of both macrophages and neutrophils to AECs. PMID:26351298
25. miR-141, as a novel repressor of ICAM-1, is involved in the attenuation of MI/R injury via antithetical regulation of ICAM-1 and inflammatory cell infiltration. PMID:26371161
26. ICAM-1 and its localization to myofibers in muscles of mdx mice contributes to the dystrophic pathology. PMID:25728314
27. ICAM-1 expression can be visualized with in vivo molecular MRI during EAE, and provides an early tracer of disease activity. PMID:24753465
28. Anti-OX40L mAb could prolong secondary heart allograft survival based on CD40/CD40L and LFA-1/ICAM-1 blockade. PMID:25613092
29. findings reveal a novel function of ICAM-1 in osteogenesis and suggest a new molecular target to improve bone regeneration and repair in inflammatory microenvironments. PMID:24702024
30. ICAM-1 can be considered as a rapid-reacting and sustained gravity-regulated molecule in mammalian cells. PMID:25654110
31. This report provides evidence for early-stage regulation of ICAM1 by microRNAs, resulting in reduction of genital pathology associated with chlamydial infection. PMID:25865776
32. Caspase-1-independent IL-1 release mediates blister formation in autoantibody-induced tissue injury through modulation of endothelial adhesion molecules. PMID:25795756
33. cell surface levels of endothelial ICAM-1 rather than the inflammatory stimulus or blood-brain barrier integrity influence the pathway of T-cell diapedesis across the blood-brain barrier. PMID:25545837
34. Constrained ICAM-1 mobility is important for dendritic cell function, as dendritic cells expressing a high-mobility ICAM-1 mutant lacking the cytoplasmic domain exhibit diminished antigen-dependent conjugate formation and T cell priming. PMID:25666808
35. Our results indicate that nicotine can enhance the expression of ICAM-1 and VCAM-1 on mouse cardiac vascular endothelial cell via p38 MAPK signaling pathway, resulting in increased expression of the cellular adhesion molecules ICAM-1 and VCAM-1. PMID:25803997
36. ICAM-1 expression by skeletal muscle cells augments myogenesis, and establish a novel mechanism through which the inflammatory response facilitates growth processes in skeletal muscle. PMID:25281303
37. RAGE and ICAM-1 are required for the anti-inflammatory functions of protein C PMID:24876676
38. ICAM-1 has a role in polymicrobial sepsis; its blockade modulates neutrophil migration and reversing immunosuppression PMID:24891762
39. Transmigrated neutrophils in the intestinal lumen engage ICAM-1 to regulate the epithelial barrier and neutrophil recruitment. PMID:24345805
40. altered expression of ICAM-1 on thymic epithelium shifts autoimmunity specifically toward peripheral nerves. PMID:25108020
41. Hydrogen peroxide exposure upregulates ICAM-1 expression in skeletal muscle. PMID:24333630
42. Data suggest that PGE2/Ep4 (prostaglandin E receptor 4; Ptger4) signaling via cAMP/Epac (exchange protein directly activated by cAMP 1; Rapgef3) induces expression of Icam1 (intercellular adhesion molecule 1) in cerebrovascular endothelial cells. PMID:23317035
43. These data indicate that L-selectin plays a major role in the development of C protein induced polymyositis, whereas ICAM-1 plays a lesser role, if any. PMID:24644046
44. TNF-alpha-induced MMP-9 expression may contribute to the production of sICAM-1 by MC3T3-E1 cells. PMID:24502696
45. pretreatment with C66 not only significantly reduced high glucose (HG)-induced over-expressions of VCAM-1, ICAM-1 and MCP-1, but also remarkably inhibited NF-kappaB activation, MAPKs phosphorylation PMID:24260158
46. ICAM-1 is imperative for inducing regulatory T cells to produce IL-10 in vivo, which would prevent granuloma formation. PMID:24103557
47. Data suggest that ICAM-1 isoforms have unique roles in experimental autoimmune encephalomyelitis (EAE). PMID:24435747
48. These studies demonstrate that ICAM-1 immunobiology is highly complex but that individual isoforms, aside from the full-length molecule, make significant contributions to disease development and pathogenesis. [review] PMID:24795464
49. Downregulation of ICAM-1 mitigates MC38 colonic adenocarcinoma invasion. PMID:24360118
50. beta2 integrin-mediated neutrophil crawling on endothelial ICAM-1 and ICAM-2 is a prerequisite for transcellular neutrophil diapedesis across the inflamed BBB. PMID:24259506

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UNIGENE: Mm.435508

KEGG: mmu:15894

STRING: 10090.ENSMUSP00000083587