Mouse Complement C2(C2) ELISA kit

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Code: CSB-EL003658MO

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Size:

96T,5×96T,10×96T

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Quantity:

Sample Types: serum, plasma, tissue homogenates

Detect Range: 18.75 ng/mL-300 ng/mL

Sensitivity: 18.75 ng/mL

Trial Size:

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Product Details
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Target Background

Product Details

Alternative Names

C2Complement C2 ELISA Kit; EC 3.4.21.43 ELISA Kit; C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment] ELISA Kit

Abbreviation

Uniprot NO.

P21180

Species

Mus musculus (Mouse)

Sample Type

serum, plasma, tissue homogenates

Detection Range

18.75 ng/mL-300 ng/mL

Sensitivity

18.75 ng/mL

Assay Time

1-5h

Sample Loading Volume

50-100ul

Detection Wavelength

450 nm

Research Area

Immunology

Assay Principle

quantitative
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Measurement

Competitive

Storage

Store at 2-8°C. Please refer to protocol.

Shelf Life

6 months

Lead Time

3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Troubleshooting and FAQs

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ELISA Data Analysis

ELISA Standard Curve & Curve Expert software

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Mouse Complement C2(C2) ELISA kit

Description

This Mouse Complement C2 (C2) ELISA Kit was designed for the quantitative measurement of Mouse Complement C2 (C2) protein in serum, plasma, tissue homogenates. It is a Competitive ELISA kit, its detection range is 18.75 ng/mL-300 ng/mL and the sensitivity is 18.75 ng/mL.

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Citations

Integrative cross‐tissue analysis unveils complement‐immunoglobulin augmentation and dysbiosis‐related fatty acid metabolic remodeling during mammalian aging F Zhang, R Li, Y Liu, J Liang, Y Gong, C Xiao, J Cai,/,2025

Target Background

Function(From Uniprot)

Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.

Gene References into Functions

Data indicate that activation of C5 in experimental cerebral malaria likely occurs via coagulation enzymes of the extrinsic protease pathway. PMID:22689574
The more pronounced lack of complement activation in Bf/C2-/- mice leads to uncontrolled infection due to an opsonophagocytic defect PMID:18672286

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Subcellular Location

Secreted.

Protein Families

Peptidase S1 family

Database Links

UNIGENE: Mm.283217

KEGG: mmu:12263

STRING: 10090.ENSMUSP00000025230

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