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Human Bone morphogenetic protein 3B(GDF10) ELISA kit

Human Bone morphogenetic protein 3B(GDF10) ELISA kit

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Code: CSB-EL009343HU

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Size:

96T,5×96T,10×96T

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Quantity:

Sample Types: serum, plasma, tissue homogenates

Detect Range: 23.5 pg/mL-1500 pg/mL

Sensitivity: 5.8 pg/mL

Trial Size:

24T ELISA Kit Trial Size (Only USD$150/ kit)
* Sample kit cost can be deducted as a $30 credit for each 96-assay kit of the same analyte and brand you subsequently purchase within six months until depleted. More details >>

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Target Background

Product Details

Alternative Names

BIP ELISA Kit; BMP 3b ELISA Kit; BMP-3b ELISA Kit; BMP3B ELISA Kit; BMP3B_HUMAN ELISA Kit; Bone inducing protein ELISA Kit; Bone morphogenetic protein 3b [Precursor] ELISA Kit; Bone morphogenetic protein 3b ELISA Kit; Bone-inducing protein ELISA Kit; GDF 10 ELISA Kit; GDF-10 ELISA Kit; Gdf10 ELISA Kit; growth differentiation factor 10 ELISA Kit; Growth/differentiation factor 10 ELISA Kit

Abbreviation

GDF10

Uniprot NO.

P55107

Species

Homo sapiens (Human)

Sample Type

serum, plasma, tissue homogenates

Detection Range

23.5 pg/mL-1500 pg/mL

Sensitivity

5.8 pg/mL

Assay Time

1-5h

Sample Loading Volume

50-100ul

Detection Wavelength

450 nm

Research Area

Signal Transduction

Assay Principle

quantitative
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Measurement

Sandwich

Storage

Store at 2-8°C. Please refer to protocol.

Shelf Life

6 months

Lead Time

3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Troubleshooting and FAQs

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ELISA Data Analysis

ELISA Standard Curve & Curve Expert software

Description

This Human GDF10 ELISA Kit was designed for the quantitative measurement of Human GDF10 protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 23.5 pg/mL-1500 pg/mL and the sensitivity is 5.8 pg/mL.

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Target Background

Function(From Uniprot)

Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhibitory role in the process of adipogenesis.

Gene References into Functions

Study shows that GDF10 is down-regulated in patients with oral squamous cell carcinoma, and is an independent risk factor for overall survival. Its expression is regulated by TGFBR3 which shares the signaling inhibiting epithelial-mesenchymal transition. PMID:25728212
GDF10 is a stroke-induced signal for axonal sprouting and functional recovery. PMID:26502261
new hypoxia-inducible and SOX9-regulated genes, Gdf10 and Chm-I. In addition, Mig6 and InhbA were induced by hypoxia, predominantly via HIF-2alpha PMID:18077449
BMP3b and BMP6 genes were suppressed by DNA methylation and methylation of BMP3b is significantly frequent in Japanese malignant pleural mesotheliomas (MPMs), suggesting its pathogenic role and the ethnic difference in MPMs. PMID:18949431