mscL Antibody

Code: CSB-PA358693ZA01FSG

Rate （N/A）
Review （0）

Size:

0.1ml

0.1ml1ml

Pls inquire

Quantity:

Species Reactivity: Mycobacterium tuberculosis

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

Send an Inquiry

Start an on-line Chat

Online ordering is currently available for U.S. customers only. For orders outside the U.S., please kindly submit an inquiry or start a chat with us.

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Uniprot NO.

P9WJN5

Target Names

mscL

Alternative Names

Large-conductance mechanosensitive channel, mscL

Raised in

Rabbit

Species Reactivity

Mycobacterium tuberculosis

Immunogen

Recombinant Mycobacterium tuberculosis mscL protein

Immunogen Species

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Conjugate

Non-conjugate

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (12-14 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Datasheet & COA

Antibody FAQs

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Channel that opens in response to stretch forces in the membrane lipid bilayer. The force required to trigger channel opening depends on the nature of the membrane lipids; the presence of phosphatidylinositol enhances mechanosensitivity of the channel. May participate in the regulation of osmotic pressure changes within the cell.

Gene References into Functions

Results show the interaction of lipids with MscL using atomistic molecular dynamics simulations and identify the simple motif that confers MscL with strong anchoring to the bilayer. PMID:25437007
residues in the primary gate in the first transmembrane domain of MscL are critical for mechanosensitive channel gating PMID:15111403
Data show that solubilization of membrane proteins such as the MscL by covalent attachment of amphiphiles results in homogeneous particles that may prove useful for crystallization, solution NMR spectroscopy, and electron microscopy. PMID:15465059
very efficient hydrophobic matching between the protein and the surrounding lipid bilayer PMID:15823029
binding site of high affinity for anionic phospholipids PMID:15823046