SMC3 Antibody

Code: CSB-PA294606XA01DOA

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Arabidopsis thaliana

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

Q56YN8

Target Names

SMC3

Alternative Names

SMC3 antibody; TTN7 antibody; At2g27170 antibody; T22O13.6 antibody; Structural maintenance of chromosomes protein 3 antibody; SMC protein 3 antibody; SMC-3 antibody; Chromosome segregation protein SMC-3 antibody; Cohesin complex subunit SMC-3 antibody; Protein TITAN7 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana SMC3 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement. Essential protein plant viability. Required for chromosome segregation (e.g. sister chromatid alignment) and cell division during embryogenesis.

Subcellular Location

Nucleus. Cytoplasm. Nucleus matrix. Chromosome. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere. Note=Primarily associated with the nuclear matrix during interphase and with chromatin from prophase through anaphase in both somatic and meiotic cells. During mitosis and meiosis the protein also colocalized with the spindle from metaphase to telophase.

Protein Families

SMC family, SMC3 subfamily

Tissue Specificity

Mostly expressed in flower buds and leaves, and, to a lower extent, in roots and stems.

Database Links

UNIGENE: At.28786

KEGG: ath:AT2G27170

STRING: 3702.AT2G27170.1

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