RYR2 Antibody

Code: CSB-PA020620XA01RB

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Oryctolagus cuniculus (Rabbit)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P30957

Target Names

RYR2

Alternative Names

RYR2 antibody; Ryanodine receptor 2 antibody; RYR-2 antibody; RyR2 antibody; Cardiac muscle ryanodine receptor antibody; Cardiac muscle ryanodine receptor-calcium release channel antibody; Cardiac muscle-type ryanodine receptor antibody; Type 2 ryanodine receptor antibody

Raised in

Rabbit

Species Reactivity

Oryctolagus cuniculus (Rabbit)

Immunogen

Recombinant Oryctolagus cuniculus (Rabbit) RYR2 protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. Required for cellular calcium ion homeostasis. Required for embryonic heart development. The calcium channel activity is modulated by formation of heterotetramers with RYR3.

Subcellular Location

Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Sarcoplasmic reticulum.

Protein Families

Ryanodine receptor (TC 1.A.3.1) family, RYR2 subfamily

Tissue Specificity

Heart and brain.

Database Links

UNIGENE: Ocu.1832

STRING: 9986.ENSOCUP00000016860

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