Rab3 Antibody

Code: CSB-PA326528XA01DLU
Size:
0.1ml
0.1ml1ml
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Quantity:
Species Reactivity: Drosophila melanogaster (Fruit fly)
Raised in: Rabbit
Application: ELISA, WB (ensure identification of antigen)
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Product Details

Uniprot NO.
Target Names
Rab3
Alternative Names
Rab3 antibody; CG7576 antibody; Ras-related protein Rab-3 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Rab3 protein
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Lead Time
Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Datasheet & COA

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
Gene References into Functions
  1. This study demonstrated that the Rab3-GEF Controls Active Zone Development at the Drosophila Neuromuscular Junction. PMID:27022630
  2. Findings suggest that Rab3 controls the distribution of active zone components via a vesicle docking mechanism that is consistent with standard Rab protein function. PMID:26317909
  3. Rab3 regulates basal synaptic strength and short-term plasticity at the level of release probability at individual sites. PMID:21378971
  4. The data of this study defined roles for Rab3-GAP and Rab3 in synaptic homeostasis and uncover a mechanism, acting at a late stage of vesicle release, that opposes the progression of homeostatic plasticity. PMID:21338884
  5. This study showed that the small GTPase Rab3 controls the protein composition and release probability of individual active zones at the Drosophila neuromuscular junction. PMID:20005823

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Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
Protein Families
Small GTPase superfamily, Rab family
Database Links

UNIGENE: Dm.2584

KEGG: dme:Dmel_CG7576

STRING: 7227.FBpp0087352

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