Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Value-added Deliverables
① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive;
Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
Gene References into Functions
This study demonstrated that the Rab3-GEF Controls Active Zone Development at the Drosophila Neuromuscular Junction.PMID:27022630
Findings suggest that Rab3 controls the distribution of active zone components via a vesicle docking mechanism that is consistent with standard Rab protein function.PMID:26317909
Rab3 regulates basal synaptic strength and short-term plasticity at the level of release probability at individual sites.PMID:21378971
The data of this study defined roles for Rab3-GAP and Rab3 in synaptic homeostasis and uncover a mechanism, acting at a late stage of vesicle release, that opposes the progression of homeostatic plasticity.PMID:21338884
This study showed that the small GTPase Rab3 controls the protein composition and release probability of individual active zones at the Drosophila neuromuscular junction.PMID:20005823