PXN Antibody

Code: CSB-PA876508XA01DOA

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0.1ml

0.1ml1ml

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Species Reactivity: Arabidopsis thaliana

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

O04200

Target Names

PXN

Alternative Names

PXN antibody; APEM3 antibody; At2g39970 antibody; T28M21.13 antibody; Peroxisomal nicotinamide adenine dinucleotide carrier antibody; Peroxisomal NAD carrier antibody; Peroxisomal membrane protein 38; antibody; PMP36) antibody; AtPMP38 antibody; Protein ABERRANT PEROXISOME MORPHOLOGY 3 antibody; Solute carrier family 25 member 17 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana PXN protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Mediates the NAD(+) import into peroxisomes. Favors the NAD(+)(in)/AMP(out) antiport exchange, but is also able to catalyze a low unidirectional transport that might be essential under special conditions. Transports CoA, dephospho-CoA, acetyl-CoA, adenosine 3',5'-diphosphate (PAP), NAD(+), AMP, ADP and NADH, but has no activity with ATP, GTP, GDP, NADPH, NADP(+) or FAD. Required for peroxisomes proliferation.

Gene References into Functions

PXN acts as a NAD/AMP transporter.PXN imports cytosolic NAD into plant peroxisomes. PXN was not able to function as a CoA transporter or a redox shuttle by mediating a NAD/NADH exchange. PMID:27208243
APEM3/PMP38 plays a role distinct from that of AtPNC1 and AtPNC2. PMP38 belongs to the mitochondrial carrier family protein. Defect of PMP38 causes enlargement of peroxisomes.[PMP38] PMID:22034551
At2g39970 delivers NAD(+) for optimal fatty acid degradation during storage oil mobilization. PMID:21895810

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Subcellular Location

Glyoxysome membrane; Multi-pass membrane protein.

Protein Families

Mitochondrial carrier (TC 2.A.29) family

Tissue Specificity

Expressed in cotyledons, hypocotyls, vascular tissues, trichomes, hydathodes, seeds, pedicels, flowers and stigma.

Database Links

UNIGENE: At.14666

KEGG: ath:AT2G39970

STRING: 3702.AT2G39970.1

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