PRF1 Antibody

Code: CSB-PA677077XA01DOA

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Arabidopsis thaliana

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

Q42449

Target Names

PRF1

Alternative Names

PRF1 antibody; PFN1 antibody; PRO1 antibody; At2g19760 antibody; F6F22.21 antibody; Profilin-1 antibody; AtPROF1 antibody; AthPRF1 antibody; allergen Ara t 8 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana PRF1 protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Binds ACT1, ACT7 and ACT11 and inhibits actin polymerization. Coordinates the stochastic dynamic properties of actin filaments by modulating formin-mediated actin nucleation and assembly during axial cell expansion. Binds G-actin and poly-L-proline in vitro. Inhibits cell growth of various pathogenic fungal strains. May play a role as antifungal proteins in the defense system against fungal pathogen attacks.

Gene References into Functions

PRF1 coordinates the stochastic dynamic properties of actin filaments by modulating formin-mediated actin nucleation and assembly during plant cell expansion. PMID:26574597
formed a filamentous network likely associated with actin filaments PMID:19200149

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Subcellular Location

Cytoplasm, cytoskeleton. Cytoplasm.

Protein Families

Profilin family

Tissue Specificity

Expressed at low levels roots, leaves, stems, flowers and siliques. Expressed in leaf epidermal cells, trichomes and stem epidermal cells. Detected in phloem exudates (at protein level).

Database Links

UNIGENE: At.23712

KEGG: ath:AT2G19760

STRING: 3702.AT2G19760.1

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