Pdk1 Antibody

Code: CSB-PA894764XA01DLU

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Size:

0.1ml

0.1ml1ml

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Quantity:

Species Reactivity: Drosophila melanogaster (Fruit fly)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

Q9W0V1

Target Names

Pdk1

Alternative Names

Pdk1 antibody; Pk61C antibody; CG1210 antibody; 3-phosphoinositide-dependent protein kinase 1 antibody; dPDK-1 antibody; EC 2.7.11.1 antibody; Serine/threonine-protein kinase 61C antibody; dSTPK61 antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) Pdk1 protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Serine/threonine kinase required for embryonic development. Inhibits apoptosis. Acts in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and activating Akt1 and S6k. May be involved in axonal pathfinding and synaptogenesis, and in spermatogenesis.

Gene References into Functions

PDK1 is also a presynaptic protein, though it is distributed more broadly. PMID:21930778
dS6K activity is dependent on the Drosophila homologue of the phosphoinositide-dependent protein kinase 1, dPDK1 PMID:11862217

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Subcellular Location

Cytoplasm.

Protein Families

Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily

Database Links

UNIGENE: Dm.7033

KEGG: dme:Dmel_CG1210

STRING: 7227.FBpp0305420

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