comt Antibody

Code: CSB-PA343978XA01DLU

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Drosophila melanogaster (Fruit fly)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P46461

Target Names

comt

Alternative Names

comt antibody; Nsf antibody; Nsf1 antibody; CG1618 antibody; Vesicle-fusing ATPase 1 antibody; EC 3.6.4.6 antibody; N-ethylmaleimide-sensitive fusion protein 1 antibody; NEM-sensitive fusion protein 1 antibody; Protein comatose antibody; Vesicular-fusion protein NSF1 antibody; dNsf-1 antibody; NSF-1 antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) comt protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

Gene References into Functions

This study illustrated the comatose mutations in protein trafficking and synaptic vesicles function. PMID:22817636
Mutants Of NSF have been engineered that define key residues involved in two essential, but mechanistically distinct, biochemical functions of NSF: SNAP binding and SNAP-dependent ATPase stimulation. PMID:11955072
Results establish in vivo contributions of SNAP-25 and NSF to synaptic vesicle trafficking and define molecular mechanisms determining conserved functional properties of short-term depression. PMID:19706552

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Subcellular Location

Cytoplasm.

Protein Families

AAA ATPase family

Tissue Specificity

Nervous system.

Database Links

UNIGENE: Dm.1772

KEGG: dme:Dmel_CG1618

STRING: 7227.FBpp0305521

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