Myb Antibody

Code: CSB-PA356215XA01DLU

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Drosophila melanogaster (Fruit fly)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P04197

Target Names

Myb

Alternative Names

Myb antibody; CG9045 antibody; Myb protein antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) Myb protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Datasheet & COA

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Target Background

Function(From Uniprot)

DNA-binding protein that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In follicle cells, the complex plays a central role in the site-specific DNA replication at the chorion loci. During development, the complex represses transcription of developmentally controlled E2F target genes.

Gene References into Functions

Myb transcriptionally regulates cytokinesis. PMID:23438598
Dm myb and grim are both involved in regulating PCD in two distinct settings suggests that these two genes may often work together to mediate PCD. PMID:22960039
Dampened transcriptional activation by E2F1-DP and Myb-MuvB is important to repress mitosis and coordinate the endocycle transcription. PMID:21045111
controls G2/M progression by inducing cyclin B expression PMID:11847115
findings imply that Dm-Myb provides an essential nontranscriptional function during chromosomal replication PMID:12032301
Drosophila myb exerts opposing effects on S phase, promoting proliferation and suppressing endoreduplication. PMID:12223407
Role for a Drosophila Myb-containing protein complex in site-specific DNA replication PMID:12490953
DmMyb activates a repressive complex containing Mip130 into a complex competent to support DNA replication at specific loci in a temporally and developmentally proscribed manner. PMID:15256498
examination of linking together the Myb and E2F2 complexes in higher-order assembly to specific chromosomal sites for the regulation of transcription PMID:15545624
The essential roles of Myb are executed as part of a switching mechanism that is dependent on DNA sites and developmental context. PMID:17978103
Cell cycle specific degradation of Drosophila Myb is likely to be utilized as a key regulatory mechanism in down-regulating the activity of the Myb complex. PMID:18424081