ITGB8 Antibody

Code: CSB-PA011892ZA01RB

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Oryctolagus cuniculus

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P26013

Target Names

ITGB8

Alternative Names

Integrin beta-8, ITGB8

Raised in

Rabbit

Species Reactivity

Oryctolagus cuniculus

Immunogen

Recombinant Oryctolagus cuniculus ITGB8 protein

Immunogen Species

Oryctolagus cuniculus (Rabbit)

Conjugate

Non-conjugate

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (12-14 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs). Required during vasculogenesis.

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Families

Integrin beta chain family

Tissue Specificity

Placenta, kidney, brain, ovary, uterus and in several transformed cells.

Database Links

UNIGENE: Ocu.1889

KEGG: ocu:100009141

STRING: 9986.ENSOCUP00000001898

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