HMGB1 Antibody

Code: CSB-PA523735XA01DOA

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Arabidopsis thaliana

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

O49595

Target Names

HMGB1

Alternative Names

HMGB1 antibody; HMGA antibody; HMGALPHA antibody; NFD01 antibody; NFD1 antibody; ORF13 antibody; At3g51880 antibody; ATEM1.13 antibody; High mobility group B protein 1 antibody; High mobility group protein A antibody; AtHMGalpha antibody; HMG alpha antibody; Nucleosome/chromatin assembly factor group D 01 antibody; Nucleosome/chromatin assembly factor group D 1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana HMGB1 protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Datasheet & COA

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Target Background

Function(From Uniprot)

Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses.

Gene References into Functions

Results show not only HMGB1 was associated with interphase but also with metaphase chromosomes in Arabidopsis. PMID:26270959
AtHMGB1 does not affect telomerase activity and AtHMGB1 loss or overexpression does not cause any obvious changes in chromatin architecture. PMID:21348847
The subcellular localization of Arabidopsis thaliana HMGA, HMGB1, and HMGB5, reveals that they localize to the cell nucleus. They display a speckled distribution pattern throughout the chromatin of interphase nuclei. PMID:17114349
The lack and overexpression of HMGB1 affect certain aspects of plant growth and stress tolerance and it has a marked impact on the transcriptome. PMID:18822296