Gucy2c Antibody

Code: CSB-PA010053ZA01RA

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Rattus norvegicus

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P23897

Target Names

Gucy2c

Alternative Names

Gucy2c antibody; Guc2c antibody; Heat-stable enterotoxin receptor antibody; STA receptor antibody; EC 4.6.1.2 antibody; Guanylyl cyclase C antibody; GC-C antibody; Intestinal guanylate cyclase antibody

Raised in

Rabbit

Species Reactivity

Rattus norvegicus

Immunogen

Recombinant Rattus norvegicus Gucy2c protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (12-14 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin.

Gene References into Functions

these studies provide a comprehensive description of Ugn and GC-C expression in the kidney of the Sprague-Dawley rat. PMID:21106860
the role of the linker region in receptor guanylyl cyclases PMID:19648115

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Subcellular Location

Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Protein Families

Adenylyl cyclase class-4/guanylyl cyclase family

Tissue Specificity

Intestine and possibly at low levels in additional tissues.

Database Links

UNIGENE: Rn.10931

KEGG: rno:25711

STRING: 10116.ENSRNOP00000012212

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