Gpc4 Antibody

Code: CSB-PA009706ZA01MO
Size:
0.1ml
0.1ml1ml
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Quantity:
Species Reactivity: Mus musculus
Raised in: Rabbit
Application: ELISA, WB (ensure identification of antigen)
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Product Details

Uniprot NO.
Target Names
Gpc4
Alternative Names
Gpc4 antibody; Glypican-4 antibody; K-glypican) [Cleaved into: Secreted glypican-4] antibody
Raised in
Rabbit
Species Reactivity
Mus musculus
Immunogen
Recombinant Mus musculus Gpc4 protein
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen Affinity Purified
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Lead Time
Made-to-order (12-14 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Value-added Deliverables
Unmodified
Datasheet & COA

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system.
Gene References into Functions
  1. Glypican 4 induces release of neuronal pentraxin 1 from presynaptic terminals. PMID:29024665
  2. Findings establish that Gpc4 acts at the interface of extrinsic and intrinsic signal regulation to fine tune stem cell fate. PMID:22761013
  3. data identify glypicans as a family of novel astrocyte-derived molecules that are necessary and sufficient to promote glutamate receptor clustering and receptivity and to induce the formation of postsynaptically functioning CNS synapses PMID:22722203
  4. complex pattern of glypican-4 mRNA localization at embryonic days 7-10.5, including sites in the anterior forebrain neuroepithelium, branchial arches, optic and otic vesicles, limb buds and somites PMID:15830372

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Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.; [Secreted glypican-4]: Secreted, extracellular space.
Protein Families
Glypican family
Tissue Specificity
Highly expressed in developing brain and kidney.
Database Links

UNIGENE: Mm.1528

KEGG: mmu:14735

STRING: 10090.ENSMUSP00000033450

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