gag Antibody

Code: CSB-PA365912XA01FBA

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Feline sarcoma virus (strain McDonough)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P03340

Target Names

gag

Alternative Names

gagGag polyprotein antibody; Core polyprotein) [Cleaved into: Matrix protein p15 antibody; MA); RNA-binding phosphoprotein p12 antibody; pp12); Capsid protein p30 antibody; CA); Nucleocapsid protein p10 antibody; NC-gag)] antibody

Raised in

Rabbit

Species Reactivity

Feline sarcoma virus (strain McDonough)

Immunogen

Recombinant Feline sarcoma virus (strain McDonough) gag protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release.; Matrix protein p15 targets Gag and gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex.; Capsid protein p30 forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.

Subcellular Location

[Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor.; [Matrix protein p15]: Virion.; [Capsid protein p30]: Virion.

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