gag Antibody

Code: CSB-PA357147XA01MCJ

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Mason-Pfizer monkey virus (MPMV) (Simian Mason-Pfizer virus)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P07567

Target Names

gag

Alternative Names

gag antibody; Gag polyprotein antibody; Core polyprotein antibody; Pr78) [Cleaved into: Matrix protein p10; Phosphorylated protein pp24; Phosphorylated protein pp18; p12; Capsid protein p27; Nucleocapsid protein p14; p4] antibody

Raised in

Rabbit

Species Reactivity

Mason-Pfizer monkey virus (MPMV) (Simian Mason-Pfizer virus)

Immunogen

Recombinant Mason-Pfizer monkey virus (MPMV) (Simian Mason-Pfizer virus) gag protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Matrix protein.; Nucleocapsid protein.; capsid protein.

Gene References into Functions

In the in-vivo experiments, the Mason-Pfizer monkey virus matrix protein did not co-localize with lipid rafts. Therefore, the authors concluded that Mason-Pfizer monkey virus might adopt a different membrane binding mechanism than HIV-1. PMID:27725181
Authors provide biochemical data confirming the critical role of the Mason-Pfizer monkey virus CA-NC spacer peptide-like domain in immature particle assembly, release, processing, and infectivity. PMID:25275119
determined the solution structure of myristoylated Mason-Pfizer monkey virus matrix protein by NMR spectroscopy and provide a detailed insight into the molecular basis of its interaction with the plasma membrane PMID:22863803
These data highlight the importance of a region containing alternating leucines and isoleucines within p12 for gag oligomerization. PMID:17490704
Thus, basic amino acids in the M-PMV membrane-proximal surface of the matrix (MA) protein component of the Gag polyprotein define both cellular location and efficiency of virus release. PMID:17596311