FMRFaR Antibody

Code: CSB-PA893353XA01DLU

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Size:

20μl50μl100μl

US$83

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Species Reactivity: Drosophila melanogaster (Fruit fly)

Application: ELISA, WB

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Product Details
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Target Background

Product Details

Uniprot NO.

Q9VZW5

Target Names

FMRFaR

Alternative Names

FMRFamide receptor (DFR) (DrmFMRFa-R) (Larval opioid receptor) FR FMRFaR CG2114

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) FMRFaR protein (398-549aa)

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Affinity-chromatography

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

ELISA, WB

Protocols

ELISA Protocol Western Blotting(WB) Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western Blot
Positive WB detected in: recombinant protein
All lanes: FMRFaR Antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 23 kDa
Observed band size: 23 kDa

Description

The FMRFaR polyclonal antibody is produced by immunizing a rabbit with a recombinant Drosophila melanogaster (Fruit fly) FMRFaR protein (amino acids 398-549). The FMRFaR antibody is extracted from the rabbit serum and then purified using affinity chromatography. The functionality of the FMRFaR antibody is assessed through ELISA and WB assays, confirming its proficiency in recognizing the Drosophila melanogaster (Fruit fly) FMRFaR protein in experimental settings.

The FMRFaR protein in Drosophila melanogaster functions as a G protein-coupled receptor responsive to neuropeptides containing the FMRFamide sequence. Neuropeptides binding to FMRFaR activate intracellular signaling pathways, influencing diverse physiological processes in fruit flies, including the modulation of feeding behavior such as food intake and digestion. Additionally, FMRFaR is implicated in reproductive processes, playing a role in the regulation of reproductive behaviors and fertility.

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Target Background

Function(From Uniprot)

A receptor for the FMRFamide peptides. Reacts with high affinity to FMRFamide and intrinsic FMRFamide-related peptides. By stimulating intracellular calcium signaling through the inositol 1,4,5-trisphosphate receptor, Itpr, in dopaminergic neurons, may be involved in the maintenance of neuronal excitability and in the regulation of flight bout duration.

Gene References into Functions

molecular cloning and expression of FMRFamide receptor PMID:12218185
The functionally active Drosophila melanogaster FMRFamide receptor (DrmFMRFa-R)was cloned and characterized. It is the first functionally active FMRFamide G protein-coupled receptor described in invertebrates to date. PMID:12438685

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 1 family

Tissue Specificity

Expressed in ovaries, heads and bodies. Expressed in dopaminergic neurons.

Database Links

UNIGENE: Dm.14721

KEGG: dme:Dmel_CG2114

STRING: 7227.FBpp0072850

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