FDX1 Antibody

Code: CSB-PA008570ZA01BO

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Bos taurus

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P00257

Target Names

FDX1

Alternative Names

FDX1 antibody; ADX antibody; Adrenodoxin antibody; mitochondrial antibody; Adrenal ferredoxin antibody; Ferredoxin-1 antibody; Hepato-ferredoxin antibody

Raised in

Rabbit

Species Reactivity

Bos taurus

Immunogen

Recombinant Bos taurus FDX1 protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (12-14 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage to produce pregnenolone, the precursor of most steroid hormones. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons.

Gene References into Functions

Data indicate that the autodisplayed adrenodoxin (Adx) showed reversible redox reactions via direct electron transfer to the mercaptoundecanoic acid (MUA)-modified gold electrode. PMID:25858110
Kinetic and optical biosensor study of adrenodoxin mutant AdxS112W displaying an enhanced interaction towards the cholesterol side chain cleavage enzyme (CYP11A1). PMID:21526428

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Subcellular Location

Mitochondrion matrix.

Protein Families

Adrenodoxin/putidaredoxin family

Tissue Specificity

Detected in adrenal cortex and corpus luteum (at protein level).

Database Links

UNIGENE: Bt.1573

KEGG: bta:281157

STRING: 9913.ENSBTAP00000015660

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