CHMP1A Antibody

Code: CSB-PA190126XA01DOA

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Arabidopsis thaliana

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

Q8LE58

Target Names

CHMP1A

Alternative Names

CHMP1A antibody; VPS46.1 antibody; At1g17730 antibody; F11A6.7ESCRT-related protein CHMP1A antibody; Protein CHARGED MULTIVESICULAR BODY PROTEIN 1A antibody; Protein CHROMATIN MODIFYING PROTEIN 1A antibody; Vacuolar protein-sorting-associated protein 46.1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana CHMP1A protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Involved in ESCRT-dependent multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Mediates the MVB sorting of the auxin carriers PIN1, PIN2 and AUX1. Required for embryonic axis establishment and seedling growth. Required for autophagic degradation of plastid proteins. Promotes the efficient sequestration of cargo from plastids into autophagosomes. Mediates the efficient delivery of autophagic plastid bodies to the vacuole, but not into the cytoplasm.

Gene References into Functions

CHARGED MULTIVESICULAR BODY PROTEIN1 (CHMP1A) and CHMP1B are required for autophagic degradation of plastid proteins in Arabidopsis thaliana. PMID:25649438
Arabidopsis thaliana ESCRT-related charged multivesicular body protein/chromatin modifying protein1A(CHMP1A) and CHMP1B proteins are essential for embryo and seedling development. [CHMP1B] PMID:19304934

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Subcellular Location

Cytoplasm. Endosome membrane; Peripheral membrane protein.

Protein Families

SNF7 family

Database Links

UNIGENE: At.41817

KEGG: ath:AT1G17730

STRING: 3702.AT1G17730.1

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