Cdc42 Antibody

Code: CSB-PA334771XA01DLU

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Drosophila melanogaster (Fruit fly)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P40793

Target Names

Cdc42

Alternative Names

Cdc42 antibody; CG12530Cdc42 homolog antibody; EC 3.6.5.2 antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) Cdc42 protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Datasheet & COA

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Target Background

Function(From Uniprot)

Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt and Frl, regulates photoreceptor cell morphogenesis. Together with Frl, has a role in the neuronal development of mushroom bodies.

Gene References into Functions

Cdc42 controls protrusion formation in a cell non-autonomous manner. PMID:28143705
Cdc42 regulates binding of Crumbs protein to the Par-6 CRIB-PDZ module. PMID:26894406
We propose that the guanine nucleotide exchange factor GEFmeso is involved in a developmental process that requires the synergistic action of CDC42 and Rac1 during Drosophila development PMID:25753922
A proof-of-principle experiment in which the Cdc42 GTPase associates with its alleged partner WASp within neurons during the time and space that coincide with the newly developing CNS. PMID:24586421
The distinct buttoning mechanism we propose for dorsal vessel closure is elaborated through signaling pathways regulating Cdc42 activity in this cell type. PMID:24949939
Zir is necessary to activate the Rho-family GTPases Rac2 and Cdc42 during the Drosophila cellular immune response. PMID:22634526
Wsp activity in within the fly testis is mediated by the small GTPase Cdc42. PMID:21652648
Drosophila Rich (dRich), a conserved Cdc42-selective guanosine triphosphatase-activating protein (GAP), inhibits the Cdc42-Wsp pathway to stimulate postsynaptic Gbb release PMID:21041451
Recruitment of Cdc42 and Rac1 to the sites of filopodium and lamellipodium formation is Rab35 dependent and occurs by way of microtubule tracks. PMID:20065041
ACK family tyrosine kinase activity is a component of Dcdc42 signaling during dorsal closure in Drosophila melanogaster. PMID:11997505
Cdc42 is a regulator for multiple aspects of dendritic development in Drosophila PMID:12716918
Both Rac1 and Cdc42 activation induced large growth cones and long filopodia, but Cdc42 did so more efficiently than Rac1. Cdc42 is specifically involved in the regulation of actin filaments in growth cones. PMID:14750960
Rho GTPases may have partially overlapping functions during planar cell polarity generation PMID:17616927
Synaptic growth activated by growth factor signaling is controlled at an endosomal compartment via coordinated Nwk and Cdc42-dependent actin assembly. PMID:18701694
The Par complex acts as an effector for Cdc42 in controlling the endocytosis of apical proteins. PMID:19064670
we propose that Ephexin/Cdc42 couples synaptic Eph signaling to the modulation of presynaptic CaV2.1 channels PMID:19249276
study showed Cdc42 remains inactive in embryos during the 1st two-thirds of embryogenesis; in the central nervous system where Cdc42 activity first becomes upregulated, individual neurons display patterns restricted to specific subcellular compartments PMID:19498173
Cdc42 antagonizes Rho1 activity at adherens junctions to limit epithelial cell apical tension. PMID:19805632