ADAMTS20 Antibody

Code: CSB-PA001309XA01HU

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Homo sapiens (Human)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P59510

Target Names

ADAMTS20

Alternative Names

ADAMTS20A disintegrin and metalloproteinase with thrombospondin motifs 20 antibody; ADAM-TS 20 antibody; ADAM-TS20 antibody; ADAMTS-20 antibody; EC 3.4.24.- antibody

Raised in

Rabbit

Species Reactivity

Homo sapiens (Human)

Immunogen

Recombinant Homo sapiens (Human) ADAMTS20 protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

May play a role in tissue-remodeling process occurring in both normal and pathological conditions. May have a protease-independent function in the transport from the endoplasmic reticulum to the Golgi apparatus of secretory cargos, mediated by the GON domain.

Gene References into Functions

In summary, this study provides genetic evidence for a role of ADAMTS20 in CL/P development in dogs and as a candidate gene for CL/P development in humans. PMID:25798845
ADAMTS-9 and ADAMTS-20 have an identical modular structure, are distinct in possessing 15 thrombospondin type I repeats and a unique C-terminal domain, and have a similar gene structure PMID:12514189
This protein is identified and characterized and its relation to other disintegrins and thrombospondin 1 repeats is examined. PMID:12562771

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Subcellular Location

Secreted, extracellular space, extracellular matrix.

Tissue Specificity

Very sparingly expressed, although is detected at low levels in testis, prostate, ovary, heart, placenta, lung and pancreas. Overexpressed in several brain, colon and breast carcinomas.

Database Links

HGNC: 17178

UNIGENE: Hs.287554

KEGG: hsa:80070

STRING: 9606.ENSP00000374071

OMIM: 611681

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