app Antibody

Code: CSB-PA580984XA01DLU

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Drosophila melanogaster (Fruit fly)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

A2VEY9

Target Names

app

Alternative Names

app antibody; CG42318Palmitoyltransferase app antibody; EC 2.3.1.225 antibody; Protein approximated antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) app protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Palmitoylates Dlish which is required for the apical cell cortex localization, total cellular level and full activity of dachs.

Gene References into Functions

Consistent with its role in Psn processing, hibris genetically interacts with the Drosophila beta-amyloid protein precursor-like (Appl) protein. PMID:22814602
These results suggest that Abeta accumulation depletes presynaptic and axonal mitochondria, leading to other presynaptic deficits. PMID:20107079

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Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.

Protein Families

DHHC palmitoyltransferase family, ERF2/ZDHHC9 subfamily

Tissue Specificity

Detected in embryo, imaginal disks and pupal wings (at protein level). Enriched in the somatic musculature and gut throughout embryonic development.

Database Links

UNIGENE: Dm.5785

KEGG: dme:Dmel_CG42318

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