ACE2 Antibody

Code: CSB-PA325032XA01SVG

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P21192

Target Names

ACE2

Alternative Names

ACE2 antibody; YLR131C antibody; L3123 antibody; L9606.10Metallothionein expression activator antibody

Raised in

Rabbit

Species Reactivity

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Immunogen

Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ACE2 protein

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Plays a role in regulating basal-level expression of CUP1. Activates EGT2 transcription in the absence of SWI5.

Gene References into Functions

ACE2, a transcription factor required for septum destruction after cytokinesis, is a negative regulator of ethanol tolerance. PMID:29789541
Therefore, Ace2 and Swi5 are two negative regulators of ethanol yield during static fermentation of yeast cells, and both CTS1 and RPS4a are major effectors mediating these two transcription factors in regulating ethanol production. PMID:26975390
Data show that mutation of the Rts1 regulatory subunit of PP2A phosphatase (PP2ARts1 phosphatase) results in decreased HO endonuclease expression due to altered localization of the Ace2 transcription factor. PMID:25352596
Genome duplication and mutations in ACE2 cause multicellular, fast-sedimenting phenotypes in evolved Saccharomyces cerevisiae. PMID:24145419
show that Ace2 asymmetry is initiated in the elongated, but undivided, anaphase nucleus PMID:22711697
Data show that Ace2's nuclear localization is maintained by continuous Cbk1 activity and that inhibition of the kinase leads to immediate loss of phosphorylation and export to the cytoplasm. PMID:20573982
Regulation of CLN3 expression by Ace2 and Ash1 can account for the differential regulation of Start in response to cell size in mothers and daughters. PMID:19841732
Phosphorylation of the C-terminal site of Cbk1 is regulated over the cell cycle and requires Ace2 as well as all RAM network components.Ace2 is not only a downstream target of Cbk1 but also reinforces activation of its upstream regulator. PMID:17145962
In the daughter cell nucleus Cbk1p phosphorylates the Ace2p nuclear export signal, and the phosphorylation blocks the export of Ace2p via Crm1p. PMID:18076379
the precise timing of Ace2 accumulation in the nucleus involves both a nuclear export sequence and a nuclear localization signal, whose activities are regulated by phosphorylation PMID:18292088