Abbreviation
Recombinant Mouse Cxcl10 protein (Active)
Purity
>97% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU/μg as determined by LAL method.
Activity
Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 0.1- 10.0 ng/ml in the presence of IL-2.
Alternative Names
Cxcl10; Crg2; Ifi10; Inp10; Scyb10C-X-C motif chemokine 10; 10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; C7; Interferon-gamma induced protein CRG-2; Small-inducible cytokine B10
Species
Mus musculus (Mouse)
Expression Region
22-98aa
Target Protein Sequence
IPLARTVRCN CIHIDDGPVR MRAIGKLEII PASLSCPRVE IIATMKKNDE QRCLNPESKT IKNLMKAFSQ KRSKRAP
Note: The complete
sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is
translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application,
please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full Length of Mature Protein
Tag Info
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Buffer
0.2 μm filtered 2×PBS, pH 7.4 ,lyophilized
Lead Time
5-10 business days
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Datasheet & COA
Please contact us to get it.
Description
CXCL10 (IP-10) is a key interferon-γ–inducible chemokine that drives CXCR3-dependent T-lymphocyte trafficking, making it central to studies of antiviral immunity, tumor microenvironment remodeling, and inflammatory disease models. This tag-free recombinant mouse CXCL10, encompassing the full-length mature sequence (residues 22–98) produced in *E. coli*, demonstrates potent chemotactic activity on human peripheral blood lymphocytes at 0.1–10.0 ng/mL in the presence of IL-2, providing a reliable basis for chemotaxis and migration assays, CXCR3 signaling pathway dissection (including MAPK and JAK/STAT activation), and dose–response standardization in cytokine detection platforms. Endotoxin levels below 1.0 EU/μg minimize LPS-driven artifacts that can confound immune cell functional readouts, which supports use in primary T-cell activation assays, *in vivo* syngeneic mouse inflammation or tumor models, and as a positive control or immunogen for antibody development and validation—all backed by >97% purity that satisfies the stringency expected in quantitative cell-based experiments.
