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Recombinant Human Protein FAM19A2 protein (FAM19A2) (Active)

Recombinant Human Protein FAM19A2 protein (FAM19A2) (Active)

CSB-AP001021HU

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US$142

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Express system: E.coli

Species: Homo sapiens (Human)

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Target Background

Product Details

Purity

>95% as determined by SDSPAGE.

Endotoxin

Less than 1.0 EU/μg as determined by LAL method.

Activity

Fully biologically active when compared to standard. The biological activity is determined by its ability to enhance neurite outgrowth of E16?E18 rat embryonic cortical neurons. rHuTAFA?2, immobilized at 6?24 μg/mL on a 96 well plate, is able to significantly enhance neurite outgrowth.

Uniprot NO.

Q8N3H0

Research Area

Immunology

Alternative Names

Chemokine like protein TAFA 2; Chemokine-like protein TAFA-2; Chemokine-like protein TAFA2; DKFZp761E1217; DKFZp781P0552; F19A2_HUMAN; FAM19A2; family with sequence similarity 19 (chemokine (C-C motif)-like); member A2; MGC42403; Protein FAM19A2; TAFA 2; TAFA2

Species

Homo sapiens (Human)

Source

E.coli

Expression Region

31-131aa

Target Protein Sequence

ANHHKAHHVK TGTCEVVALH RCCNKNKIEE RSQTVKCSCF PGQVAGTTRA APSCVDASIV EQKWWCHMQP CLEGEECKVL PDRKGWSCSS GNKVKTTRVT H

Mol. Weight

11.2 kDa

Protein Length

Full Length of Mature Protein

Tag Info

Tag-Free

Buffer

Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Lead Time

5-10 business days

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

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Recombinant Human Protein FAM19A2 protein (FAM19A2) (Active)

Description

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Target Background

Function

Has a role as neurotrophic factor involved in neuronal survival and neurobiological functions.

Gene References into Functions

Data identified two, BCL2 and FAM19A2, novel loci and replicated known variants associated with insulin sensitivity. Further studies are needed to clarify the causal variant and function at the BCL2 and FAM19A2 loci. PMID:27416945
Variants of FAM19A2 (rs348644) are associated with forced expiratory volume in COPD. PMID:25112515
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID:20379614
Observational study of gene-disease association. (HuGE Navigator) PMID:19240061