TSC1

Hamartin is a protein in humans that is encoded by TSC1 gene. In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

The following TSC1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TSC1 Antibodies

TSC1 Proteins

TSC1 Antibodies

TSC1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA025113GA01HU	TSC1 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA849764LA01HU	TSC1 Antibody	Human	ELISA, IHC, IF
CSB-PA849764LB01HU	TSC1 Antibody, HRP conjugated	Human	ELISA
CSB-PA849764LC01HU	TSC1 Antibody, FITC conjugated	Human
CSB-PA849764LD01HU	TSC1 Antibody, Biotin conjugated	Human	ELISA
CSB-RA048528A0HU	TSC1 Recombinant Monoclonal Antibody	Human	ELISA, WB, IF, FC

TSC1 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA790048XA01SXV	tsc1 Antibody	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ELISA, WB (ensure identification of antigen)

TSC1 Proteins

TSC1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP849764HU CSB-EP849764HU CSB-BP849764HU CSB-MP849764HU CSB-EP849764HU-B	Recombinant Human Hamartin (TSC1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP849764HU	Recombinant Human Hamartin (TSC1), partial	E.coli

TSC1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP863631MO CSB-EP863631MO CSB-BP863631MO CSB-MP863631MO CSB-EP863631MO-B	Recombinant Mouse Hamartin (Tsc1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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