SMAD7

Mothers against decapentaplegic homolog 7 is a protein in humans that is encoded by SMAD7 gene. Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

The following SMAD7 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

SMAD7 Antibodies

SMAD7 Proteins

SMAD7 Antibodies

SMAD7 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA950035	SMAD7 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA324386	SMAD7 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA021793LA01HU	SMAD7 Antibody	Human	ELISA, WB, IF
CSB-PA021793LB01HU	SMAD7 Antibody, HRP conjugated	Human	ELISA
CSB-PA021793LC01HU	SMAD7 Antibody, FITC conjugated	Human
CSB-PA021793LD01HU	SMAD7 Antibody, Biotin conjugated	Human	ELISA

SMAD7 Proteins

SMAD7 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP021793RA CSB-EP021793RA CSB-BP021793RA CSB-MP021793RA CSB-EP021793RA-B	Recombinant Rat Mothers against decapentaplegic homolog 7 (Smad7)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SMAD7 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP021793HU CSB-EP021793HU CSB-BP021793HU CSB-MP021793HU CSB-EP021793HU-B	Recombinant Human Mothers against decapentaplegic homolog 7 (SMAD7)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SMAD7 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP021793MO CSB-EP021793MO CSB-BP021793MO CSB-MP021793MO CSB-EP021793MO-B	Recombinant Mouse Mothers against decapentaplegic homolog 7 (Smad7)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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