MYL3 Antibody

Code: CSB-PA015310DSR1HU

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Size:

20μl50μl100μl

US$83

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Species Reactivity: Human, Mouse, Rat

Raised in: Rabbit

Application: ELISA, WB, IHC

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Target Background

Product Details

Uniprot NO.

P08590

Target Names

MYL3

Alternative Names

Cardiac myosin light chain 1 antibody; CMH8 antibody; CMLC1 antibody; ELC of myosin antibody; Essential light chain of myosin antibody; MLC1SB antibody; MLC1V antibody; MYL3 antibody; MYL3_HUMAN antibody; Myosin light chain 1 antibody; Myosin light chain 1 slow twitch muscle B/ventricular isoform antibody; Myosin light chain 1 slow, B antibody; Myosin light chain 3 antibody; Myosin, light chain 1, ventricular antibody; myosin, light chain 3, alkali, ventricular, skeletal, slow antibody; myosin, light polypeptide 3, alkali antibody; myosin, light polypeptide 3, alkali, ventricular, skeletal, slow antibody; OTTHUMP00000165922 antibody; Slow skeletal ventricular myosin alkali light chain 3 antibody; slow-twitch muscle B/ventricular isoform antibody; Ventricular/slow twitch myosin alkali light chain antibody; VLC1 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human Myosin light chain 3 protein (1-195AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western blot
All lanes: MYL3 antibody at 3.78 μg/ml
Lane 1: Mouse heart tissue
Lane 2: Mouse skeletal muscle tissue
Lane 3: Rat heart tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 22 kDa
Observed band size: 22 kDa
Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA015310DSR1HU at dilution of 1:100

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Target Background

Function(From Uniprot)

Regulatory light chain of myosin. Does not bind calcium.

Gene References into Functions

In Familial Hypertrophic Cardiomyopathy, the MYL3 Arg94His variant was associated with high disease penetrance and substantial interventricular septal hypertrophy PMID:26443374
N-fragment is the binding domain of human ventricular LC1, whereas the C-fragment serves as a functional domain, which may be more involved in the modulation of the actin-activated ATPase activity of myosin PMID:14516912
Cell-permeable peptide containing the 15 amino acid N-terminal peptide from human ventricular light chain-1 (VLC-1) enhanced myocardial contractility. PMID:17717642

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Database Links

HGNC: 7584

UNIGENE: Hs.517939

KEGG: hsa:4634

STRING: 9606.ENSP00000292327

OMIM: 160790

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