LILRB2 Antibody

Code: CSB-PA006212

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Size:

50μg100μg

US$119

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Species Reactivity: Human

Raised in: Rabbit

Application: WB, ELISA

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Target Background

Product Details

Uniprot NO.

Q8N423

Target Names

LILRB2

Alternative Names

CD85 antigen-like family member D antibody; CD85d antibody; CD85d antigen antibody; ILT 4 antibody; ILT-4 antibody; ILT4 antibody; Immunoglobulin like transcript 4 antibody; Immunoglobulin-like transcript 4 antibody; Leukocyte immunoglobulin like receptor 2 antibody; Leukocyte immunoglobulin like receptor subfamily B member 2 antibody; Leukocyte immunoglobulin-like receptor 2 antibody; Leukocyte immunoglobulin-like receptor subfamily B member 2 antibody; Leukocyte immunoglobulin-like receptor; subfamily B (with TM and ITIM domains); member 2 antibody; LILRA6 antibody; LILRB2 antibody; LIR 2 antibody; LIR-2 antibody; LIR2 antibody; LIRb antibody; LIRB2_HUMAN antibody; MIR 10 antibody; MIR-10 antibody; MIR10 antibody; Monocyte/macrophage immunoglobulin like receptor 10 antibody; Monocyte/macrophage immunoglobulin-like receptor 10 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human CD85d.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Tested Applications

WB, ELISA

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

Western Blot analysis of HeLa cells using CD85d Polyclonal Antibody

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Target Background

Function(From Uniprot)

Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Tissue Specificity

Expressed in monocytes and at lower levels in myeloid and plasmacytoid dendritic cells. Expressed in tolerogenic IL10-producing dendritic cells. Expressed in myeloid-derived suppressor cells during pregnancy. Detected at low levels in natural killer (NK)

Database Links

HGNC: 6606

UNIGENE: Hs.655652

STRING: 9606.ENSP00000375629

OMIM: 604815

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