ABCF1 Antibody

CSB-PA554269

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Size:

100μl

US$297

Quantity:

Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: ELISA,WB

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Product Details
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Target Background

Product Details

Uniprot NO.

Q8NE71

Target Names

ABCF1

Alternative Names

ABC27 antibody; ABC50 antibody; ABCF1 antibody; ABCF1_HUMAN antibody; ATP binding cassette 50 (TNF alpha stimulated) antibody; ATP binding cassette 50 antibody; ATP binding cassette sub family F member 1 antibody; ATP binding cassette; sub family F (GCN20); member 1 antibody; ATP-binding cassette 50 antibody; ATP-binding cassette sub-family F member 1 antibody; AU041969 antibody; D17Wsu166e antibody; EST123147 antibody; GCN20 antibody; TNF alpha stimulated ABC protein antibody; TNF-alpha-stimulated ABC protein antibody; TNFalpha inducible ATP binding protein antibody; wu:fb79c06 antibody; wu:fc39a05 antibody; wu:fj94a08 antibody; zgc:85667 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from C-terminal of Human ABCF1.

Immunogen Species

Homo sapiens (Human)

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Tested Applications

ELISA,WB

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Protocols

ELISA Protocol Western Blotting(WB) Protocol

Datasheet & COA

Antibody FAQs

Images

Western blot analysis of extracts from HeLa/COLO205 cells, using ABCF1 antibody.

Description

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Target Background

Function

Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.

Gene References into Functions

The high copy number variant in the ABCF1 gene was the strongest risk factor for gout. PMID:28405828
ABCF1 extrinsically regulates retinal pigment epithelial cell phagocytosis of shed photoreceptor outer segments. PMID:25904329
Elevated microRNA-23a Expression Enhances the Chemoresistance of Colorectal Cancer Cells with Microsatellite Instability to 5-Fluorouracil by Directly Targeting ABCF1 PMID:25929864
expression of ABC50 mutants, which cannot hydrolyse ATP, decreases general translation and relaxes the discrimination against the use of non-AUG codons at translation start sites. PMID:25597744
A rare copy number variation of the ABCF1 gene was detected among dengue patients from Malaysia. PMID:24634119
The results suggested that SNPs at PRR3 and ABCF1 genes and the haplotype composed by SNPs at GNL1 and PRR3 between the HLA-A and HLA-C genes tended to predict Graves ophthalmology in a gender-dependent manner in patients with Graves disease in Taiwan. PMID:24908204
ABCF1 showed a significant increase in expression after escitalopram treatment. PMID:23719290
ABCF1 is a critical protein that associates with viral double-stranded DNA. PMID:23263557
The two critical HLA regions for susceptibility to autoimmune pancreatitis are limited to the HLA-DRB1*0405-DQB1*0401 in the class II and the ABCF1in the class I regions. PMID:17119950
ABC50 N-terminal region interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2 PMID:17894550
ABC50 plays a key role in translation initiation and has functions that are distinct from those of other non-membrane ABC proteins. PMID:19570978